If not for the 1st couple's seme, the uke would have been in deeper shit when he's on heat with some other alphas around. Seme also managed to change uke gradually and uke starts to think more of the future.
Though not a couple, 1st seme's father saved 2nd uke by taking him in, thereby saving him from the harsh life that awaits a poor, in debt, abandoned omega.
Physically: Uke beat off some guys to save seme and kitten
Chapter 1 & 2: Ruffian-like uke saved timid seme from harrassment
Physically: Side couple 1
Emotionally: Both the uke and seme need each other to save them from their emptiness.
Chapter 7: Used-to-be-abused older uke x Gentle younger seme
Uke saved seme from freezing to death in the streets; Seme saved uke from his abusive ex-boyfriend.
Seme saved uke from sexual assault; uke saved seme from his own dark self
Uke saved seme from the lifestyle he's leading and seme saved uke from the trauma he carried with him. Both of them helped each other to find their way back as they become closer. It's a really beautiful and touching relationship.
Abarenbo honey