Though it doesn't advertise this fact, Yuri Danshi-kun is the 4-koma-esque spin-off of Yuri Danshi (http://www.mangago.me/read-manga/yuri_danshi/bt/302602/Vol1_Ch1/). Yuri Danshi (the original) is much talkier, with traditional paneling, but also stars Hanadera Keisuke as a high school boy obsessed with yuri. In some ways, Yuri Danshi-kun is a meta-joke: Yuri Danshi takes fujoshi characters like Tama from Barakamon and makes them into yuri-obsessed fudanshi who see yuri-undertones in every casual girl-on-girl interaction. The tropes about the pure, barely sexual, and completely idealized relationships in yuri give a World Only God Knows vibe to Yuri Danshi. Yuri Danshi-kun, on the other hand, panders straight back to the Tama's of the manga-reading world. Hanadera, along with a handful of other male yuri fans, are thrown into a bizarre alternate world where there are no women at all -- and thus, obviously, no yuri. So the parody of the parody becomes the thing parodied in the first parody -- not confusing at all!
I think part of the reason why Yuri Danshi-kun may seem so confusing is that I rather suspect the other guys in Yuri Danshi-kun are characters we meet later in Yuri Danshi, and Yuri Danshi-kun assumes we're familiar with their personalities and interactions. Once you get around to figuring out who is who (not an easy feat, as everyone shares the same SD-face and there are two megane characters, one of whom shares a haircut with a non-megane character), the jokes are relatively stand-alone and entertaining, but I strangely find myself more interested in the mechanics of this alt-universe, like where DO babies come from?!
Yuri Danshi-kun