Big Spoiler, dont read if u still want to read the manga to the End. Since I just explained what happend in the raws until chapter 45 (the end)
They are not siblings, rather they were raised together. From the beginning, the King had twins and since twin were a bad omen, one of them was send away with the maid. The Maid was Hisuis Mother, so she and her husband raised them as siblings, but due to the poor health of the twin, who stayed in the palace.... the other twin had to be brought back and so, one of the inner generals, made it look like bandits took killed hisuis parents and took her brother, so he was taken back to the palace and was raised as a double of the Majesty. But this neither the king or queen knew about it.
So basically they are not blood-related.
Are they brother and sister or not?