Well, Sangwoo in '' Semantic Error '' is probably high functionning autistic / asperger . So not really ' disabled ' , but he shows very rigid and black and white thinking, and he's rather asocial, not anti social but has lack of empathy and gets in trouble sometimes for being super blunt.
(But you probably know that manhwa already ?) The comedic aspect comes from the contrast with his partner-to-be , as they are polar opposites to each others. So we get to see the good sides of working together with Sangwoo and his humour too.
This one is a beautiful (school life) friendship between two guys with different level of abilities, but they meet on the same wavelength a lot of the time, and that's really nice. I love the mood and, you can see it as Shounen Ai coded. https://www.mangago.me/read-manga/kimi_to_uchuu_wo_aruku_tame_ni/
https://www.mangago.me/read-manga/i_cant_even_breeth_without_you/
I've always thought the mangaka in this is on the spectrum.

Is there any yaoi where one of them is a bit mentally disable (Autism syndrome) and his partner falls in love with him? I recently watched "Extraordinary attorney Woo" and was thinking if there is any yaoi like this