Some characters that were introduced in Omega complex will be shown in Alpha trauma as side characters, if that’s important for you to learn about them then yes!
But learning some basic information will get you through Alpha trauma just fine. It depends on how you’re going to take the information
If I got spoiled from the beginning I wouldn’t have touched omega complex at all to be honest because I personally don’t like it that much

I heard this is a sequel so do I need to read Omega Complex before this? And if I end up reading that after this one, will it ruin my view of the main characters? :3