Responses
Mademoiselle butterfly
koizora
bambi to dhole
Kiss and harmony
Kimi ni shika kikoenai
Dengeki daisy
Taiyou no uta
Watashitachi no shiawase na jikan
49
One word for you buddy...(NANA) It'll wreck you, change you, and haunt you forever. (And..it doesn(t just have one female lead...it has TWO).
I also second "Orange". (but it concentrates on a male character, not female, give it a try though, I liked it)
Good, heart wrenching shoujo recommendations! Preferably female leeeaddd