Ch.1-4 - Konatsu is an independent omega who ends up reuniting with her childhood friend, Prime Minister Konatsu. Though she feels their statuses are too different for them to be together, he's certain they're meant to be. Trigger warnings: sex work, discrimination.
Ch.5-9 - Kayama is a "betafied" omega who releases almost no pheromones, but when two alphas see her in heat, they decide to attack her anyway. She's saved by a janitor but then she loses her jobs and never gets to see him again. Until years later, her savior reappears at the bar she works at looking like a whole new man! Trigger warnings: discrimination, attempted rape.
Ch.9-11 - Rune lives in a dystopian future where alphas and omegas are raised completely separately and partners and family size are decided by AI, but one day she wanders into the alpha side of the school on accident. She's saved by alpha Horo and falls in love at first sight, but there's almost no chance they'll ever meet again, until by chance they're paired together on the day of their graduation. Trigger warning: sexual harassment.
Hatsujou Omega ni Unmei wa Hizamazuku